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Ask Dr. Paul - Tea and Health Information5/2/2008 from DASH - Hi.  A friend, who is re-doing her pantry, recently asked me whether she should throw away a whole bunch of old tea bags (some many years old)...

Ask Dr. Paul - Tea and Health Information3/28/2008 from Mrs. P - About 6 years ago, the stiffness all over my body, interfered with my daily activities.  After numerous tests, whch were inconclusive, I was put...


News & Views
#89c - 9/08/08
Will EGCG of green tea help inhibit breast cancer cell growth?
#89b - 9/08/08
Will mate tea protect unsaturated fatty acids from oxidation?
#89a - 9/08/08
Will oolong tea contain as much EGCG as green tea?
#88c - 9/01/08
Is green tea protective against cardiovascular disease?
#88b - 9/01/08
Will green tea manufactured from mature leaves contain more EGCG than tea manufactured from young leaves? How much EGCG is in partially fermented tea?
#88a - 9/01/08
Will green tea reduce LDL oxidability and improve vascular function in women?
#87c - 8/25/08
Will aluminum migrate into the tea marketed in aluminum cans?
#87b - 8/25/08
Can green tea reduce free iron-caused oxidative stress in the circulating blood?
#87a - 8/25/08
Will ECg of green tea reduce atherosclerosis-related foam cell formation?
#86c - 8/18/08
Is green tea more protective against cardiovascular disease in women than in men?
#86b - 8/18/08
Will tea improve attention task performance better than coffee?
#86a - 8/18/08
Will tea reduce the incidence of diabetes?
#85b - 8/11/08
Is tea protective against age-associated cognitive dysfunction in humans?
#85a - 8/11/08
Are tea polyphenols protective against acrylamide?
#84b - 8/04/08
Is topically applied green tea extract protective against UV light skin damage?
#84a - 8/04/08
Is caffeine protective to the fetus through the placenta?
#83b - 7/28/08
Is green tea EGCG protective against endometriosis?
#83a - 7/28/08
Is EGCG of green tea protective against pulmonary fibrosis?
#82c - 7/21/08
Will tea reduce folic acid bioavailability?
#82b - 7/21/08
Will green tea polyphenols, Vitamin E and Vitamin C work synertistically as antioxidants?
#82a - 7/21/08
Are green tea polyphenols protective against radiation damage?
#81c - 7/14/08
Will Pu-erh tea help lower blood cholesterol levels?
#81b - 7/14/08
Will green tea catechins make chemotherapeutic agents more effective?
#81a - 7/14/08
Is green tea EGCG an effective prostate cancer inhibitor?
#80c - 7/07/08
Is green tea effective against bone loss?
#80b - 7/07/08
Will green tea foster endothelial cell (artery lining) health?
#80a - 7/07/08
Is green tea ointment effective against anogenital warts?
#79b - 6/30/08
Is green tea EGCG prophylactic for Alzheimer's disease?
#79a - 6/30/08
Will green tea reduce obesity?
#78b - 6/23/08
Is green tea protective against lung cancer?
#78a - 6/23/08
Will green tea lower blood cholesterol levels?
#77c - 6/16/08
Can we easily moniter pesticide residues in tea before marketing?
#77b - 6/16/08
Is black tea an effective anti-arthritis agent?
#77a - 6/16/08
Will certain foods including grapes facilitate EGCG absorption?
#76N - 6/9/08
Is theanine a brain cell protective agent?
#76 - 6/9/08
Will theanine protect the brain from environmental toxins?
#75N - 6/2/08
Are black tea theaflavins protective against breast cancer?
#75 - 6/2/08
Green tea and soy: will they combine to lower cholesterol levels?
#74N - 5/26/08
Will green tea EGCG protect against Alzheimer's disease?
#74 - 5/26/08
What fungi are needed to manufacture Puer tea?
#73N - 5/19/08
Will theanine both suppress appetite and improve memory?
#73 - 5/19/08
Are green tea polyphenols cytostatic agents?
#72 - 5/12/08
Will mate tea reduce lung inflammation and oxidation in cigarette smokers?
#71N - 5/5/08
Will both drinking tea and cigarette smoking deter Parkinson's disease?
#71 - 5/5/08
Will green tea EGCG deter lung cancer metastasis?
#70N - 4/28/08
Will EGCG deter breast cancer by inducing antioxidant enzymes in breast cells?
#70 - 4/28/08
Will both cinnamon and green tea help regulate immune and inflammation function?
#69 - 4/21/08
Will green tea help prevent ovarian cancer?
#68F - 4/17/08
Will black tea paired with vegetables and fruits protect the diabetic from hypertension?
#68N - 4/14/08
Will Vitamin C counterbalance the iron-restricting effects of tea?
#68 - 4/14/08
Will tea help fight worm infections?
#67N - 4/7/08
Will drinking green tea reduce mouth odors?
#67 - 4/7/08
Will green tea reduce oxidative stress related to benzene toxicity?
#66N - 3/31/08
Will green tea reduce alcohol-induced liver toxicity?
#66 - 3/31/08
Will black tea induce cancer protective phase II enzymes?
#65F - 3/24/08
Is caffeine both a stimulant and a prooxidant?
#65N - 3/24/08
If arsenic and cadmium are in the soil will they be in our tea?
#65 - 3/24/08
Will green tea catechins improve levels of fatness, blood pressure and cholesterol in children?
#64F - 3/19/08
Will green tea catechins help prevent Alzheimer's disease?
#64N - 3/17/08
Do loose leaf brewed teas contain less fluoride and aluminum than brewed bagged teas?
#64 - 3/17/08
Will oolong tea help lower blood pressure?
#63N - 3/10/08
Do green tea polyphenols serve as cell regulatory molecules?
#63 - 3/10/08
Will green tea inhibit Hepatitis B infection?
#62 - 3/3/08
Are unhealthful metallic elements present in tea?
#61N - 2/25/08
Are pesticides in tea?
#61 - 2/25/08
How does theanine work in the brain?
#60 - 2/18/08
Does caffeine consumption increase the risk of glaucoma?
#59N - 2/11/08
Will L-theanine of tea help fight colds and flu?
#59 - 2/11/08
Will black tea theaflavins sometimes reduce oxidatative stress and at other times induce oxidative stress?
#58N - 2/4/08
Will green tea EGCG help reduce cardiac and skeletal damage in acidic conditions?
#58 - 2/4/08
Will green tea strictinin stimulate immune system activity?
#57N - 1/28/08
Will black tea enhance the effectiveness of certain antibiotics?
#57 - 1/28/08
Is green tea extract effective against genital warts?
#56 - 1/21/08
Can drinking excessive amounts of instant tea cause fluorosis?
#55 - 1/14/08
Will green tea improve insulin sensitivity in obesity?
#54 - 1/7/08
Will tea reduce iron availability for red blood cell formation?
#53 - 12/31/07
Will EGCG of green tea inhibit breast cancer growth?
#52 - 12/24/07
Will drinking tea reduce carotid artery plaque in women?
#51 - 12/17/07
Is yerba mate an effective health tea?
#50 - 12/10/07
Is green tea EGCG protective against cervical cancer when combined with retinoic acid?
#49 - 12/3/07
Is black tea protective against colorectal cancer?
#48 - 11/26/07
How does the combined theanine and caffeine of tea affect cognition?
#47 - 11/19/07
Will green tea EGCG facilitate prostate cancer cell death?
#46 - 11/12/07
What happens to green tea polyphenols in our bodies?
#45 - 11/5/07
Is EGCG protective against parkinson's disease?
#44 - 10/29/07
Will green tea catechins promote insulin secretion in diabetics?
#43 - 10/22/07
Will EGCG of green tea improve islet transplants for diabetics?
#42 - 10/15/07
Will Theogallin and L-theanine alter electrical activity in the brain?
#41 - 10/08/07
Is EGCG an effective treatment for her2-positive breast cancer?
#40 - 10/01/07
Will both green and black teas inhibit prostate cancer cell growth?
#39 - 9/24/07
Can green tea advance pathogenic bacterial growth in our intestines?
#38 - 9/17/07
Can black tea help prevent weight gain?
#37 - 9/10/07
Can green tea help lower our blood sugar levels?
#36 - 9/3/07
Can green tea serve as a cell regulatory as well as an antioxidizing agent?
#35 - 8/27/07
Can oolong tea serve as a cell regulatory as well as an antioxidizing agent?
#34 - 8/20/07
Will steeping methods determine the amount of catechins and caffeine in your teacup?
#33 - 8/13/07
How does yellow tea compare to other camellia sinensis teas?
#32 - 8/6/07
Can we differentiate between white, green, oolong, black and pu-erh teas based on their amino acid content?
#31 - 7/30/07
Is rooibos tea as effective an antimutagenic agent as green tea?
#30 - 7/23/07
Is green tea simply an antioxidant or can it also regulate genetic expression?
#29 - 7/16/07
Will green tea help protect us from absorption of environmental pollutants into our bloodstreams?
#28 - 7/9/07
Will green tea promote a healthier balance between blood HDL/LDL cholesterol?
#27 - 7/2/07
Are green tea polyphenols cardioprotective? If so, how?
#26 - 6/25/07
Will EGCG help protect cells from becoming cancerous?
#25 - 6/18/07
What do we know about the potential anticarcinogenic qualities of EGCG?
#24 - 6/11/07
Will infusion time or adding milk alter the health benefits of black tea?
#23 - 6/4/07
Will mate tea benefit Parkinson's patients?
#22 - 5/28/07
Will green tea help neutralize troublesome free iron ions in the circulating blood?
#21 - 5/21/07
Will black tea theaflavins trigger apoptosis in prostate cancer cells?
#20 - 5/14/07
Will green tea polyphenols sometimes function as pro-oxidants?
#19 - 5/7/07
Will the flavonoids of tea help prevent ovarian cancer?
#18 - 4/30/07
Will green tea help prevent bone loss?
#17 - 4/23/07
Will caffeine reduce the risk of Parkinson's disease?
#16 - 4/16/07
Are black tea polyphenols protective against breast cancer?
#15 - 4/9/07
Can quantum physics help explain how green tea catechins work as antioxidants?
#14 - 4/2/07
Will mate tea cause bladder cancer?
#13 - 3/26/07
Will green tea help prevent stroke?
#12 - 3/19/07
Are green and black teas both anticarcinogenic?
#11 - 3/12/07
Will theanine alter alpha wave activity?
#10 - 3/5/07
Will green tea help ward off brain senescence?
#9 - 2/ 26/07
Will rooibos tea promote bronchodilation?
#8 - 2/19/07
Will green tea serve as an antiinflammatory agent?
#7 - 2/12/07
Will green tea help coax cancer cells to self-destruct?
#6 - 2/5/07
Will rooibos tea help stimulate antibody production?
#5 - 1/29/07
Will milk added to black tea reduce its effectiveness as a cardioprotective agent?
#4 - 1/22/07
Will green tea help slow collagen breakdown in the body?
#3 - 1/15/07
Will green tea help reduce oxidative stress?
#2 - 1/8/07
Will black tea help reduce cardiac arrhythmias after a heart attack?
#1 - 1/1/07
Will green tea help prevent gastric ulcer?




8-18-2008 Dr. Paul's Tea & Health Update #86a
WILL TEA REDUCE THE INCIDENCE OF DIABETES?

   Diabetes, particularly type 2 diabetes, is becoming epidemic in many parts of the world. Nearly 200 million people have diabetes today (about 5% of the worldwide population) and this is expected to increase to over 300 million in the next 15-20 years. Is it possible that if more of us drank tea on a regular basis that our risk of diabetes would be decreased? The following study helps answer this question.

Tea consumption may improve biomarkers of insulin sensitivity and risk factors for diabetes.
J Nutr. 2008 Aug;138(8):1584S-1588S. Stote KS, Baer DJ.
Click Here for PubMed Abstract of Study

   This review study recognizes the evidence showing that:

   "tea may affect glucose metabolism and insulin signaling..."

   It concludes that:

   "Epidemiologic studies suggest some relation between tea consumption and a reduced risk of type 2 diabetes..."

Ask your tea professional to guide you toward enjoyable tea options. Ask your health professional to guide you toward viable health options. Dr. Paul's Tea & Health Update, WWW.DRPAULSUPDATES.ORG, supports tea and health educational programs by bringing recent research studies into public awareness. - Copyright © 2008 Dr. Paul's School of Tea and Health, LLC.


8-18-2008 Dr. Paul's Tea & Health Update #86b
WILL TEA IMPROVE ATTENTION TASK PERFORMANCE BETTER THAN COFFEE?

   Tea contains both L-theanine and caffeine while coffee contains (larger amounts) only caffeine. Will the combined affect of L-theanine and caffeine improve attention task performance better than caffeine alone? The following study addresses this question.

L-theanine and caffeine in combination affect human cognition as evidenced by oscillatory alpha-band activity and attention task performance.
J Nutr. 2008 Aug;138(8):1572S-1577S. Kelly SP, et.al.
Click Here for PubMed Abstract of Study

   This study evaluated the possible modulatory effects of (1) a placebo, (2) the combination 100 mg L-theanine, 50 mg caffeine, and (3) caffeine alone on both visuspatial attention performance and alpha-band activity in human subjects. The study found:

   "an increase in hit rate and target discriminability (d') for the combined treatment relative to placebo, and an increase in d' but not hit rate for caffeine alone, whereas no effects were detected for L-theanine alone."

   The data also showed:

   "lower overall tonic alpha power in the combined treatment, similar to previous findings at a larger dosage of L-theanine alone."

Ask your tea professional to guide you toward enjoyable tea options. Ask your health professional to guide you toward viable health options. Dr. Paul's Tea & Health Update, WWW.DRPAULSUPDATES.ORG, supports tea and health educational programs by bringing recent research studies into public awareness. - Copyright © 2008 Dr. Paul's School of Tea and Health, LLC.


8-18-2008 Dr. Paul's Tea & Health Update #86c
IS GREEN TEA MORE PROTECTIVE AGAINST CARDIOVASCULAR DISEASE IN WOMEN THAN IN MEN?

   This epidemiological study examines a possible inverse relationship between green tea consumption and cardiovascular disease (CVD) in humans. It also evaluated possible differences between green tea consumption in men and women.

The relation between green tea consumption and cardiovascular disease as evidenced by epidemiological studies.
J Nutr. 2008 Aug;138(8):1548S-1553S. Kuriyama S.
Click Here for PubMed Abstract of Study

   This population-based prospective cohort study was part of the larger Ohsaki Study in over 40 thousand individuals in Northern Japan. The study found an:

   "inverse association of mortality from CVD...more pronounced in women..."

   The study results also found a:

   "stronger inverse association...for stroke mortality."

Ask your tea professional to guide you toward enjoyable tea options. Ask your health professional to guide you toward viable health options. Dr. Paul's Tea & Health Update, WWW.DRPAULSUPDATES.ORG, supports tea and health educational programs by bringing recent research studies into public awareness. - Copyright © 2008 Dr. Paul's School of Tea and Health, LLC.


8-25-2008 Dr. Paul's Tea & Health Update #87a
WILL ECg OF GREEN TEA REDUCE ATHEROSCLEROSIS-RELATED FOAM CELL FORMATION?

   Foam cell formation in the artery wall lining is a frequent, early step leading to atherosclerotic plaque formation which, in turn, leads to cardiovascular disease.
Note: ECg [(-)-Epicatechin gallate], like EGCG, is a major component of green but not black tea.
Note: Foam cells are lipid-laden (cholesterol-laden) macrophage-related cells that accumulate in the inner lining of the artery wall as part of the progression toward cardiovascular diseases such as heart attack and stroke.

(-)-Epicatechin gallate accumulates in foamy macrophages in human atherosclerotic aorta: Implication in the anti-atherosclerotic actions of tea catechins.
Biochem Biophys Res Commun. 2008 Jul 25. Kawai Y, et.al.
Click Here for PubMed Abstract of Study

   The investigators found that:

   "ECg could suppress the gene expression of a scavenger receptor CD36, a key molecule for foam cell formation, in macrophage cells."

   The results suggest that one way green tea may reduce one's risk of cardiovascular disease is that ECg may reduce macrophage-foam cell-related activity in the artery walls.

Ask your tea professional to guide you toward enjoyable tea options. Ask your health professional to guide you toward viable health options. Dr. Paul's Tea & Health Update, WWW.DRPAULSUPDATES.ORG, supports tea and health educational programs by bringing recent research studies into public awareness. - Copyright © 2008 Dr. Paul's School of Tea and Health, LLC.


8-25-2008 Dr. Paul's Tea & Health Update #87b
CAN GREEN TEA REDUCE FREE IRON-CAUSED OXIDATIVE STRESS IN THE CIRCULATING BLOOD?

   Free iron (unbound iron ions) is a frequent source of damaging free-radical formation in the circulating blood. Previous studies suggest that green tea components such as EGCG work to reduce oxidative stress in the body by both chelating with (absorbing) and scavenging (defusing) free iron ions in the circulating blood.
Note: ROS (reactive oxygen species, free radicals, oxidants) are potentially damaging, wayward energy packets and the major source of oxidative stress.
Note: GTE (green tea extract).
Note: Lipid peroxidation is an expression of ROS-related damage.

Effect of green tea on iron status and oxidative stress in iron-loaded rats.
Med Chem. 2008 Jul;4(4):365-70. Ounjaijean S, et.al.
Click Here for PubMed Abstract of Study

   This study, performed in rats, took place over a four month period. The study found that GTE:

   "can decrease iron in plasma as well as eliminate lipid peroxidation in plasma, and destroy formation of erythrocyte ROS in the rats challenged with iron."

Ask your tea professional to guide you toward enjoyable tea options. Ask your health professional to guide you toward viable health options. Dr. Paul's Tea & Health Update, WWW.DRPAULSUPDATES.ORG, supports tea and health educational programs by bringing recent research studies into public awareness. - Copyright © 2008 Dr. Paul's School of Tea and Health, LLC.


8-25-2008 Dr. Paul's Tea & Health Update #87c
WILL ALUMINIUM MIGRATE INTO THE TEA MARKETED IN ALUMINUM CANS?

   Ready-to-drink tea is increasingly being marketed in aluminum cans. For example, iced tea and green tea concentrate are marketed this way by several companies. The following study investigates whether or not the aluminum in cans gets into the tea.
Note: Most aluminum cans are lined with plastic which separates the contents of the can from the aluminum container...unless the can is damaged (dented). This plastic liner can be damaged when the aluminum can is damaged (dented).

Aluminium migration into beverages: Are dented cans safe?
Sci Total Environ. 2008 Jul 29. Verissimo MI, Gomes MT.
Click Here for PubMed Abstract of Study

   The study investigated the migration rate of aluminum from cans to tea and beer. It compared the aluminum content in these beverages after seven months of storage in undamaged and in dented cans. The investigation found that aluminum increased:

   "0.14 mg L(-1) in beer, and 0.6 mg L(-1) in tea."

   The study also found that aluminum:

   "concentration in dented canned tea increased 9.6 mg L(-1) in seven months."

Ask your tea professional to guide you toward enjoyable tea options. Ask your health professional to guide you toward viable health options. Dr. Paul's Tea & Health Update, WWW.DRPAULSUPDATES.ORG, supports tea and health educational programs by bringing recent research studies into public awareness. - Copyright © 2008 Dr. Paul's School of Tea and Health, LLC.


9-01-2008 Dr. Paul's Tea & Health Update #88a
WILL GREEN TEA REDUCE LDL OXIDABILITY AND IMPROVE VASCULAR FUNCTION IN WOMEN?

   A recent study (See #86c) suggests that green tea may be protective against cardiovascular disease especially in women. The following study examines two possible ways green tea may be protective: reducing LDL cholesterol oxidation levels in the circulating blood and improving blood flow (vascular function).

Green tea reduces LDL oxidability and improves vascular function.
J Am Coll Nutr. 2008 Apr;27(2):209-13. Tinahones FJ, et.al.
Click Here for PubMed Abstract of Study

   This study conducted in women found that:

   "consumption of green tea extract by women for five weeks produced modifications in vascular function and an important decrease in serum oxidizability."

Ask your tea professional to guide you toward enjoyable tea options. Ask your health professional to guide you toward viable health options. Dr. Paul's Tea & Health Update, WWW.DRPAULSUPDATES.ORG, supports tea and health educational programs by bringing recent research studies into public awareness. - Copyright © 2008 Dr. Paul's School of Tea and Health, LLC.


9-01-2008 Dr. Paul's Tea & Health Update #88b
WILL GREEN TEA MANUFACTURED FROM MATURE LEAVES CONTAIN MORE EGCG THAN TEA MANUFACTURED FROM YOUNG LEAVES? HOW MUCH EGCG IS IN PARTIALLY FERMENTED TEA?

   Numerous research studies suggest that EGCG (of green tea) is protective against a variety of human diseases. The following study compares EGCG content in various green and partially fermented (oolong) teas.

New Phenolic Components and Chromatographic Profiles of Green and Fermented Teas.
J Agric Food Chem. 2008 Aug 8. Lin LZ, et.al.
Click Here for PubMed Abstract of Study

   The study found that EGCG is:

   "the major phenolic component of green tea made from mature leaveswhile green tea made from the younger buds and leavescontained lower flavonoid concentrations."

   The study also found that:

   "Partially fermented teascontained one-half the EGCG content of the green tea."

Ask your tea professional to guide you toward enjoyable tea options. Ask your health professional to guide you toward viable health options. Dr. Paul's Tea & Health Update, WWW.DRPAULSUPDATES.ORG, supports tea and health educational programs by bringing recent research studies into public awareness. - Copyright © 2008 Dr. Paul's School of Tea and Health, LLC.


9-01-2008 Dr. Paul's Tea & Health Update #88c
IS GREEN TEA PROTECTIVE AGAINST CARDIOVASCULAR DISEASE?

   The following is a review study.

Green tea catechins and cardiovascular health: an update.
Curr Med Chem. 2008;15(18):1840-50. Babu PV, Liu D.
Click Here for PubMed Abstract of Study

   This study recognizes numerous scientific studies suggesting that green tea catechins may be protective against cardiovascular disease in six possible ways. Catechins may:

   "present antioxidant activity"

   "reduce intestinal lipid absorption"

   "regulate vascular tone"

   "prevent vascular inflammation"

   "inhibit proliferation of vascular smooth muscle cells"

   "suppress platelet adhesion"

Ask your tea professional to guide you toward enjoyable tea options. Ask your health professional to guide you toward viable health options. Dr. Paul's Tea & Health Update, WWW.DRPAULSUPDATES.ORG, supports tea and health educational programs by bringing recent research studies into public awareness. - Copyright © 2008 Dr. Paul's School of Tea and Health, LLC.


9-08-2008 Dr. Paul's Tea & Health Update #89a
WILL OOLONG TEA CONTAIN AS MUCH EGCG AS GREEN TEA?

   A previous study (88b) suggested that partially fermented (oxidized) tea (e.g., oolong) is likely to contain half of the EGCG as unfermented tea (e.g. green). Nevertheless, fermentation level is highly variable in oolong teas. Also, many oolong teas (typically called "old oolong teas") are heated (roasted) as part of the flavor enhancement manufacturing process. Oolong teas not heated or roasted are often called "young oolong teas." The following study examines the changes that take place in oolong tea compounds that take place during these intense heating processes.

Massive Accumulation of Gallic Acid and Unique Occurrence of Myricetin, Quercetin, and Kaempferol in Preparing Old Oolong Tea.
J Agric Food Chem. 2008 Aug 16. Lee VS, et.al.
Click Here for PubMed Abstract of Study

   One of the findings of this study was that there was:

   "significant lower (-)-epigallocatechin gallate (EGCG) but higher gallic acid contentsdetected in the old teas compared to the new one."

Ask your tea professional to guide you toward enjoyable tea options. Ask your health professional to guide you toward viable health options. Dr. Paul's Tea & Health Update, WWW.DRPAULSUPDATES.ORG, supports tea and health educational programs by bringing recent research studies into public awareness. - Copyright © 2008 Dr. Paul's School of Tea and Health, LLC.


9-08-2008 Dr. Paul's Tea & Health Update #89b
WILL MATE TEA PROTECT UNSATURATED FATTY ACIDS FROM OXIDATION?

   Mate tea (unlike green, oolong and black teas) is manufactured from the Ilex paraguariensis plant rather than the Camellia plant. Mate is a very popular tea grown and consumed throughout South America (and Central America). Several preceding studies have suggested that mate tea, similar to green tea, contains a number of effective antioxidant compounds. The following study adds to these previous studies.

Consumption of mate tea (Ilex paraguariensis) decreases the oxidation of unsaturated fatty acids in mouse liver.
Br J Nutr. 2008 Aug 19;:1-6. Martins F, et.al.
Click Here for PubMed Abstract of Study

   This study examined the possible antioxidant qualities of mate polyphenols in the bloodstreams of mice. It concludes that mate tea helps protect:

   "unsaturated fatty acids from oxidation and may have selective protective effects within the body, especially on the liver."

Ask your tea professional to guide you toward enjoyable tea options. Ask your health professional to guide you toward viable health options. Dr. Paul's Tea & Health Update, WWW.DRPAULSUPDATES.ORG, supports tea and health educational programs by bringing recent research studies into public awareness. - Copyright © 2008 Dr. Paul's School of Tea and Health, LLC.


9-08-2008 Dr. Paul's Tea & Health Update #89c
WILL EGCG OF GREEN TEA HELP INHIBIT BREAST CANCER CELL GROWTH?

   The expression of p27Kip1 is receiving increased research interest as a target gene related to breast cancer. Instability of p27Kip1 is associated with increased breast cancer growth activity. Ideally, any agent that stabilizes p27Kip1 activity will be protective against many common estrogen-sensitive forms of breast cancer.

Epigallocatechin gallate (EGCG) stabilizes p27kip1 in estrogen- stimulated MCF-7 cells through downregulation of the Skp2 protein.
Endocrinology. 2008 Aug 21. Huang HC, et.al.
Click Here for PubMed Abstract of Study

   This study examined the possible mechanism whereby EGCG may inhibit the growth of estrogen-stimulated breast cancer cells (MCF-7) in the laboratory. It found that EGCG stabilizes p27kip1 in estrogen- stimulated MCF-7 cells through downregulation of the Skp2 protein. The study concludes that:

   "therapeutic strategies designed to reduce Skp2 may...play an important clinical role in treatment of breast cancer cells."

Ask your tea professional to guide you toward enjoyable tea options. Ask your health professional to guide you toward viable health options. Dr. Paul's Tea & Health Update, WWW.DRPAULSUPDATES.ORG, supports tea and health educational programs by bringing recent research studies into public awareness. - Copyright © 2008 Dr. Paul's School of Tea and Health, LLC.
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