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May 5, 2008 Update #71 |
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WILL GREEN TEA EGCG DETER LUNG CANCER METASTASIS?
Background
Previous studies have suggested that green tea ECGC
may inhibit the growth of several types of cancer but not lung cancer.
The following study, however, asks a different question, "Will it inhibit
the lung cancer cell's ability to migrate?" Migration, of course, is
integral to metastasis.
Featured Research Study
Epigallocatechin-3-gallate (EGCG) inhibits the migratory behavior of tumor bronchial epithelial cells.
Respir Res. 2008 Apr 21;9(1):33. Hazgui S, et.al.
Click Here for PubMed Abstract of Study
Study Highlights
Using both two-dimensional (2D) and three-dimensional
(3D) models of tumor bronchial epithelial cells, cell migration rates
were assessed with and without EGCG (under 10 microgram/ml levels).
The study concluded that "EGCG is able to inhibit the migration of
bronchial tumor cells and could therefore be an attractive candidate
to treat tumor invasion and cell migration."
Comments
This study opens the possibility that EGCG of green
tea in very low concentrations may slow the cell migration rates and
therefore the metastasis rates of certain bronchial tumors. Certainly
more work is needed before we know for sure.
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Dr. Paul's Tea & Health Update, WWW.DRPAULSUPDATES.ORG, supports tea and health educational programs by bringing recent research studies into public awareness.
Copyright © 2008 Dr. Paul's School of Tea and Health, LLC. All rights reserved.
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